Vidya P Ramamurthy Selected Research

3- hydroxy- 17- (1H- benzimidazole- 1- yl)androsta- 5,16- diene

10/2019	Galeterone and The Next Generation Galeterone Analogs, VNPP414 and VNPP433-3β Exert Potent Therapeutic Effects in Castration-/Drug-Resistant Prostate Cancer Preclinical Models In Vitro and In Vivo.
8/2017	Galeterone and its analogs inhibit Mnk-eIF4E axis, synergize with gemcitabine, impede pancreatic cancer cell migration, invasion and proliferation and inhibit tumor growth in mice.
9/2015	Galeterone and VNPT55 induce proteasomal degradation of AR/AR-V7, induce significant apoptosis via cytochrome c release and suppress growth of castration resistant prostate cancer xenografts in vivo.

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Vidya P Ramamurthy Research Topics

Disease

8	Prostatic Neoplasms (Prostate Cancer) 10/2019 - 02/2015
7	Neoplasms (Cancer) 10/2019 - 01/2014
3	Neoplasm Metastasis (Metastasis) 03/2019 - 05/2017
2	Triple Negative Breast Neoplasms 03/2019 - 01/2014
2	Breast Neoplasms (Breast Cancer) 07/2014 - 01/2014
1	Disease Progression 08/2017
1	Pancreatic Neoplasms (Pancreatic Cancer) 08/2017
1	Carcinogenesis 05/2017

Drug/Important Bio-Agent (IBA)

6	Eukaryotic Initiation Factor-4EIBA 03/2019 - 01/2014
3	3- hydroxy- 17- (1H- benzimidazole- 1- yl)androsta- 5,16- dieneIBA 10/2019 - 09/2015
3	Phosphotransferases (Kinase)IBA 03/2019 - 02/2015
3	Androgen Receptors (Androgen Receptor)IBA 01/2018 - 02/2015
3	Proteins (Proteins, Gene)FDA Link 01/2018 - 01/2014
2	Therapeutic UsesIBA 10/2019 - 01/2018
2	Mitogen-Activated Protein KinasesIBA 03/2019 - 01/2018
2	Peptide Initiation Factors (Initiation Factor)IBA 05/2017 - 01/2014
1	Pharmaceutical PreparationsIBA 10/2019
1	enzalutamideIBA 10/2019
1	ChemokinesIBA 03/2019
1	4- (+;- )- (1H- imidazole- 1- yl)- N- (4- fluorophenyl)- (E)- retinamideIBA 03/2019
1	Mechanistic Target of Rapamycin Complex 1IBA 03/2019
1	CytokinesIBA 03/2019
1	Prostate-Specific Antigen (Semenogelase)IBA 01/2018
1	VimentinIBA 01/2018
1	Cadherins (E-Cadherin)IBA 01/2018
1	Dihydrotachysterol (AT 10)IBA 01/2018
1	Cyclin D1IBA 01/2018
1	Matrix Metalloproteinases (MMPs)IBA 01/2018
1	retinamideIBA 01/2018
1	CateninsIBA 01/2018
1	ClaudinsIBA 01/2018
1	Gemcitabine FDA Link 08/2017
1	AndrogensIBA 01/2017
1	Ether (Diethyl Ether)IBA 07/2016
1	Cytochromes c (Cytochrome c)IBA 09/2015
1	VNPT55IBA 09/2015
1	Letrozole (Femara)FDA LinkGeneric 07/2014
1	Aromatase (CYP19)IBA 07/2014
1	Aromatase InhibitorsIBA 07/2014
1	ThapsigarginIBA 07/2014
1	4-(1H-imidazol-1-yl)retinoic acidIBA 07/2014

Therapy/Procedure

4	Castration 10/2019 - 09/2015
4	Therapeutics 03/2019 - 01/2014